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Non-Anticoagulant Fractions of Enoxaparin Suppress Inflammatory Cytokine Release from Peripheral Blood Mononuclear Cells of Allergic Asthmatic Individuals

Fig 3

Concentration-dependent suppression of cytokine release by enoxaparin fractions.

Inhibition of cytokine release by 0 to 40 μg/ml of enoxaparin fractions 1 and 4. Cytokines [IL-4 (A), IL-5 (B), IL-13 (C) and TNF- α (D)] were released by PBMCs of allergic asthmatic subjects (n = 5) after ex-vivo stimulation with PHA. Data is presented as percentage of PHA-stimulated control. *p<0.05, **p<0.01 and ***p<0.001 versus PHA-stimulated control.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0128803.g003