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Micro-CT Technique Is Well Suited for Documentation of Remodeling Processes in Murine Carotid Arteries

Fig 1

Experimental design.

Partial ligation of the LCCA in ApoE-/- mice at day 0. Timeline of high fat diet (HFD) treatment and overview showing analysis methods. Comparison of in vivo micro-CT and histology was performed by in vivo micro-CT scan and subsequent histological examination (d7, n = 4, d14, n = 10, d28, n = 9). Comparison of in vivo micro-CT and ex vivo micro-CT was performed by in vivo micro-CT scan and subsequent perfusion with the post mortem contrast agent MicroFil (n = 5); H/E, hematoxylin/eosin.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0130374.g001