Micro-CT Technique Is Well Suited for Documentation of Remodeling Processes in Murine Carotid Arteries
Fig 4
Comparison of in vivo and ex vivo micro-CT.
Lumen area profile after partial ligation of the LCCA. (A, B) Lumen profile of the LCCA and RCCA was evaluated by in vivo (AuroVist Nanoparticles) and ex vivo (MicroFil) micro-CT at postoperative day 14 (n = 5). Lumen area was evaluated from the aortic arch (1) to the bifurcation (9). Error bars indicate the mean ± SEM. (C) Correlation between mean lumen area of LCCA and RCCA of each mouse examined by in vivo and ex vivo micro-CT. Linear regression parameters and correlation coefficients were calculated. (D) Volume rendering of the LCCA and RCCA examined by in vivo and post mortem micro-CT with corresponding visualization of the virtual elastic sphere path (grey). BA, brachiocephalic artery; LCCA, left common carotid artery; RCCA right common carotid artery; RSA, right subclavian artery branch; STA, superior thyroid artery.