Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode
Fig 4
Multiple-inhibitor experiments for the inhibition of rat brain [3H]AEA (0.5 μM) hydrolysis using carprofen and either A, B, (R)-Flu-AM1, or C, D, (S)-Ibu-AM5.
The left panels show the untransformed data and are means ± SEM, N = 3–4. The right panels show the Dixon plots of the mean data.
