Consistency Analysis of Genome-Scale Models of Bacterial Metabolism: A Metamodel Approach
Fig 2
Examples of two metabolic pathways inconsistently reconstructed.
a) The siroheme biosynthetic pathway in prokaryotes. b) The biotin biosynthetic pathway from pimelate; yellow colored metabolites indicate root deadends. Numbers in brackets refer to the total number of GSMs in which the reactions were found blocked and present, respectively. Metabolite abbreviations can be found in S3C Table.
