Flexible Sheet-Type Sensor for Noninvasive Measurement of Cellular Oxygen Metabolism on a Culture Dish
Fig 1
Schematic diagram of flexible sensor sheet.
During the measurement, the device is attached to the bottom of the culture dish to form a temporarily closed microspace around the target cells, hence enabling the short-time evaluation of oxygen consumption rate. The device comprises a transparent EVOH/PDMS sheet and an array of microchamber structures (φ 90 μm, 50 μm depth) that contain a 1-μm-thick sensing layer at their bottom.