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Flexible Sheet-Type Sensor for Noninvasive Measurement of Cellular Oxygen Metabolism on a Culture Dish

Fig 6

(a) Bright-field image of rat hippocampus slice. Scale bar: 500 μm. (b) Oxygen concentration rate mapping of rat hippocampus slice indicated with blue box in a. (c) Oxygen concentration rate mapping indicated with yellow box in a. CA1 and CA3 are pyramidal cells of the hippocampus and DG is the dentate gyrus. Broken lines show neuronal cell bodies. This result indicates that the oxygen consumption rate of DG is higher than those of CA3 and CA1, and the oxygen consumption rate around neuronal cell bodies is higher than in the molecular layers. Scale bar: 200 μm.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0143774.g006