The Cell Death Inhibitor ARC Is Induced in a Tissue-Specific Manner by Deletion of the Tumor Suppressor Gene Men1, but Not Required for Tumor Development and Growth
Fig 4
Generalized deletion of ARC in Pdx1-Cre; Men1 f/f mice does not significantly change islet tumor load.
A) Body weights (both genders). B) Fasting plasma insulin concentrations (both genders). C) Fasting blood glucose concentrations (both genders). D) and E) Fasting insulin and glucose measurements in females. F) and G) Fasting insulin and glucose measurements in males. * P < 0.05 Pdx1-Cre; Men1 f/f; ARC -/- versus Pdx1-Cre; Men1 f/f; ARC +/+.
