Long Non-Coding RNA Malat-1 Is Dispensable during Pressure Overload-Induced Cardiac Remodeling and Failure in Mice
Fig 4
Alternative splicing of Ndrg2 and Eif4h is evident after TAC.
(A) Skipping of Ndrg2 exon 3 is apparent after TAC in Malat-1 WT and KO mice, but absence of Malat-1 reduces this event both at baseline and after pressure overload. (B) Exon 5 inclusion of Eif4h is induced by TAC but not affected by absence of Malat-1. (C) Representative images of PCR products of Eif4h and Ndrg2. *p<0.05, ****p<0.0001 TAC versus Sham; $p<0.05 KO versus WT.
