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Real-Time Label-Free Embolus Detection Using In Vivo Photoacoustic Flow Cytometry

Fig 2

Images of healthy and melanoma-bearing mice during intervention.

(A) Blood congestion in healthy mouse foot during clamping. (B) Healthy mouse foot after clamp removal with no bleeding or tissue damage. (C) Melanoma tumor in the mouse ear before applying the 120 g pressure. (D) In vivo real-time PA detection of emboli during ear B16F10-tumor compression (120 g weight) in nude mouse ear. Scale bars are 0.5 cm.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0156269.g002