Tendon Reattachment to Bone in an Ovine Tendon Defect Model of Retraction Using Allogenic and Xenogenic Demineralised Bone Matrix Incorporated with Mesenchymal Stem Cells
Fig 4
Photomicrographs showing appearance of DBM allograft and xenograft at 12 weeks.
Specimens stained with Toluidine Blue and Paragon. (a) Zone 1: Patellar tendon-DBM allograft interface characterized by well-organized, crimped collagen fibres with elongated fibroblast nuclei. (b) Zone 1: Patellar tendon-DBM xenograft interface characterized by well-organized, crimped collagen fibres with elongated fibroblast nuclei. (c) Zone 2: Tendon defect with complete remodeling of DBM allograft and large areas of well-organized, crimped collagen fibres with elongated fibroblast nuclei. (d) Zone 2: Tendon defect with complete remodeling of DBM xenograft and large areas of well-organized, crimped collagen fibres with elongated fibroblast nuclei. (e) Zone 3: Allogenic DBM neo enthesis comprising tendon (T), fibrocartilage (FC), mineralized fibrocartilage (MFC) and bone (B). (f) Zone 3: Xenogenic DBM neo enthesis comprising disorganised tendon (T), fibrocartilage (FC), mineralized fibrocartilage (MFC) and bone (B).
