Exploring the Functional Complementation between Grp94 and Hsp90
Fig 2
Chimeric constructs used in this study.
Schematic representation showing the domain composition of Hsp90, Grp94, and the fragments used to create chimeras of Hsp90 and Grp94. Boundaries are shown with residue numbering for yeast Hsp90 and canine Grp94. The N-terminal chimeras referred to as grpN-hspMC (4), hspN-grpMC (3) and hspNM-grpM2C (9) were previously described in Ref. [20].