Denervation-Induced Activation of the Standard Proteasome and Immunoproteasome
Fig 6
Protein content of autophagy markers LC3 in WT and L7M1 mice with denervation.
(A-B) Results of densitometry are presented as the fold change compared to WT Day 0 for the autophagy marker LC3. Each panel contains results of two-way ANOVA that were used to detect the effect of strain (WT vs. L7M1) and time (Day 0, 7, and 14) for (A) LC3I and (B) LC3II (# indicates significant effect of strain/time/S x T interactions, p < .05). Statistical comparison showed a significant denervation (time) effect in both LC3I and LC3II content (p < .04). No strain effect or interaction was found. Values are mean ± SE. Sample size per group: n = 3–5. Representative Western blot for each protein is presented in Fig 1.
