Effect of intravenous immunoglobulin on the function of Treg cells derived from immunosuppressed mice with Pseudomonas aeruginosa pneumonia
Fig 2
Lung histopathological manifestations of the lung tissues at 8 h in each group.
Six groups were studied: Control group (A), IS group (B), PA group (C), IS + PA group (D), PA + IVIG group (E) and IS + PA + IVIG group (F). Immunosuppression was induced on day -5, -3 and -1 by intraperitoneal injection of CYP, PA pneumonia was induced on day 0 and IVIG mediated treatment models were immediately established following PA intervention on day 0. Following establishment of the models, mice were sacrificed at the 4, 8, and 24 h time points. The right lung tissue was fixed in 10% formalin, embedded in paraffin, sliced, and stained with H&E for histological analysis. Histopathological manifestations of lung tissue in six groups at 8h were shown with magnified 100 times.
