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Effect of intravenous immunoglobulin on the function of Treg cells derived from immunosuppressed mice with Pseudomonas aeruginosa pneumonia

Fig 3

Pathological score of lung tissue in each group at 4, 8 and 24h.

Six groups were studied: Control group, IS group, PA group, IS + PA group, PA + IVIG group and IS + PA + IVIG group. Immunosuppression was induced on day -5, -3 and -1 by intraperitoneal injection of CYP, PA pneumonia was induced on day 0 and IVIG mediated treatment models were immediately established following PA intervention on day 0. The right lung of the experimental mice was used for pathological analysis and scored based on a standard scoring system of acute lung injury. Pathological scores of lung tissue in six groups at 4, 8 and 24h were shown.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0176843.g003