Allele-specific DNA methylation of disease susceptibility genes in Japanese patients with inflammatory bowel disease
Fig 2
Flowchart of cis-regulating allele-specific DNA methylation SNP candidate selection around IBD susceptibility genes.
SNP, single-nucleotide polymorphism; MSRE, methylation-sensitive restriction enzyme; RAS, relative allele score; IBD, inflammatory bowel disease; (G), genomic DNA; (D), DNA digested MSREs; (U), whole-genome-amplified fully unmethylated DNA digested MSREs.