Bilateral carotid artery stenosis causes unexpected early changes in brain extracellular matrix and blood-brain barrier integrity in mice
Fig 5
Changes in glial cells are observed in multiple regions of the brain following BCAS.
A) Representative images of GFAP staining (red) within the cortex, hippocampus and striatum of sham or BCAS-treated (14 days) mice. Scale bar = 100 um. Inset images are a magnified portion to show detail. Scale bar = 300 um. B) Quantification of GFAP-positive pixels. N = 4 **p < 0.01, ***p < 0.001 C) Representative images of CD11b staining (green) within the cortex, hippocampus and striatum of sham or BCAS-treated (14 days) mice. Scale bar = 100 um. Inset images are a magnified portion to show detail. Scale bar = 300 um. D) Quantification of CD11b-positive pixels. N = 4 *p < 0.05.
