The soluble VEGF receptor sFlt-1 contributes to endothelial dysfunction in IgA nephropathy
Fig 6
Expression of cleaved-caspase 9, caspase 3, Bcl-2 and Bax in sFlt-1-induced HUVECs with or without Z-LEHD-FMK incubation.
The HUVECs were treated with the indicated concentrations of sFlt-1, and then treated with or without Z-LEHD-FMK. The protein expression levels of cleaved caspase-9, caspase-3, Bcl-2, Bax and β-actin were detected by western blotting (A). Relative protein levels of caspase-9 (B), caspase-3 (C), Bcl-2 (D) and Bax (E) versus β-actin are presented as histograms. Results are the means ± standard deviation of three independent experiments.
