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High-throughput analysis of lung immune cells in a combined murine model of agriculture dust-triggered airway inflammation with rheumatoid arthritis

Fig 10

Treatment group-specific gene expression pattern.

Demonstrated in isolated monocytes. Monocytes were sorted as CD11c, CD11bhigh. (A) Heat map of fold-change of top 15 genes/treatment group (CIA, ODE and CIA+ODE) normalized to 20 housekeeping genes compared to Sham. (B) Bar graphs depict mean with standard error bars of representative genes from each treatment group Sham (red), CIA (green), ODE (teal), and CIA+ODE (blue). N = 3 (3 independent experiments with 2–3 mice pooled, 8 total mice). *P<0.05, ****P<0.0001.

Fig 10

doi: https://doi.org/10.1371/journal.pone.0240707.g010