Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition
Fig 3
ADCC activity in ALVAC-SIV/gp120 and NYVAC-SIV/gp120 vaccinated animals.
Comparison of percent ADCC killing between pre-immunization and one week post-final immunization (week 25) in (A) 7 ALVAC and (D) 7 NYVAC-vaccinated macaques. (B,C) A positive correlation was observed between the number of intravaginal challenges and the percentage of ADCC killing or ADCC titers in ALVAC-vaccinated macaques. (E,F) Correlation analysis between the number of intravaginal challenges to infection and the percentage of ADCC killing or ADCC titers in 7 NYVAC-vaccinated macaques. Horizontal lines represent the median.
