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Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition

Fig 6

Summary of immune responses that correlated with each other and with virus acquisition.

Visual summary of data obtained in the current study (left) and two previously reported independent studies [15, 16]. Vaccine induced cells correlated directly with CD14 monocytes (indicated by arrows) and indirectly with the time of virus acquisition following vaginal (left) and rectal (panel) exposure to the same stock of SIVmac251.

Fig 6

doi: https://doi.org/10.1371/journal.ppat.1008377.g006