In Fig 1, panels B, C and D are mislabeled as D, B and C respectively. The authors have provided a corrected version here.
VAR2CSA protein sequence diversity of the seven full-length VAR2CSA ectodomain has been analysed to highlight (A) sequence identity within the seven phylogenetically distant alleles of VAR2CSA, reported in Renn et al. [12], by multiple alignment of NTS-DBL6 fragments (ranged from 2640 to 2723 amino acids) using BioEdit version 7.0.5.3 software. (B) The structure of VAR2CSA complex with PAM1.4 (PDB:7Z12) reported in Raghavan et al. [11] was used to map the PAMVAC (in blue) and PRIMVAC (in red) vaccine boundaries, while VH:VL chains of PAM1:4 are highlighted in orange and green. (C) The binding level of human monoclonal IgG PAM1.4 and (D) pooled purified IgG from multigravidae (MG) to the seven full-length VAR2CSA (Fv2) recombinants was measured by ELISA. Optical density (OD) units are reported.
Reference
- 1. Doritchamou JYA, Renn JP, Hviid L, Duffy PE (2023) A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us? PLoS Pathog 19(5): e1011370. https://doi.org/10.1371/journal.ppat.1011370 pmid:37228009
Figures
Citation: Doritchamou JYA, Renn JP, Hviid L, Duffy PE (2024) Correction: A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us? PLoS Pathog 20(1): e1011503. https://doi.org/10.1371/journal.ppat.1011503
Published: January 29, 2024
Copyright: © 2024 Doritchamou et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
